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New Urine Analyzer in Clinical Pathology


New Urine Analyzer in Clinical Pathology

As of March 13, 2014, we replaced our urine analyzer (Criterion II) with a new, different, model (Siemens Clinitek Advantus). The new model uses the same dipstick (Siemens Multistix) used in most veterinary clinics. The analyzer replacement will change our reported dipstick results on our urinalysis, in the following ways:

  1. Protein and heme: The upper limit of the reported scale is lower with the new analyzer.
  2. Glucose and ketones: The scale of reported results (and associated qualitative estimates) has changed somewhat.
  3. Bilirubin will now only be reported as a qualitative estimate, not a numerical value, i.e. small, moderate, and large.
  4. Heme will now only be reported as a qualitative estimate, not a plus value, i.e. trace, small, moderate, and large.

For more details, see comparison chart below:

Result

Advantus

Criterion

Protein

(mg/dL)

Neg

15 (trace)

30 (1+)

100 (2+)

>=300 mg/dl (3+)

Neg

15 (trace)

30 (1+)

100 (2+)

500 (3+)

Glucose

(mg/dL)

Neg

100 (trace)

250 (small)

500 (moderate)

>=1000 (large)

Neg

50 (trace)

100 (small)

250 (moderate)

≥1000 (large)

Ketones

(mg/dL)

Neg

Trace

15 (small)

40 (moderate)

>=80 (large)

Neg

5 mg/dl (trace)

15 mg/dl (small)

50 mg/dl (moderate)

≥150 mg/dl (large)

Bilirubin

Neg

Small

Moderate

Large

Neg

1 mg/dL (small)

3 mg/dL (moderate)

6 mg/dL (large)

Heme

Neg

Trace

Small

Moderate

Large

Neg

Trace

1+

2+

3+


Internal studies in our laboratory have shown that there is good association between results of the two analyzers and differences between results from the two analyzers are mild. Consistent changes are slightly higher bilirubin and lower heme reactions with the new analyzer. If you would like to see more details of these internal test comparisons, please contact Dr. Stokol.