Comparative Coagulation

The Comparative Coagulation Section of the Animal Health Diagnostic Center provides veterinarians and biomedical researchers comprehensive testing and consultation services for the diagnosis and characterization of blood coagulation disorders in animals. To fulfill this mission, the laboratory engages in basic research on mechanisms of hemostasis and thrombosis and validation of assays to examine these systems in many different species.

Dr. Marjory Brooks ( Director)
Dr. Jim Catalfamo (Emeritus)

Comparative Coagulation's unique offering of services includes the most comprehensive test menu in the country for definitive diagnosis of veterinary hemostatic disorders.

Services provided by the Comparative Coagulation Section include:

Coagulation and Fibrinolysis Testing

Coagulation screening tests
Coagulation factor assays
Fibrinolysis activators and inhibitors
D-dimer and FDP assays
Functional and quantitative fibrinogen assays

Anticoagulant and Inhibitor Assays

Protein C activity
Antithrombin activity and TAT complex
Heparin monitoring (anti-Xa activity)
Coagulation inhibitors: Bethesda and lupus anticoagulant assays

Platelet Function Testing

PFA100 screening
Aggregation and secretion studies
Flow cytometry
Platelet procoagulant assays

Von Willebrand Factor Assays

Von Willebrand factor antigen
Von Willebrand factor collagen binding

Canine and Feline Blood Typing
Consultation on Clinical and Comparative Hemostasis

Test selection and interpretation
Assay development and adaptation for special studies